Above left: A diabetic foot ulcer in the lateral metatarsal area that had been present for 14 months. This photograph was taken one week after human skin equivalent (Apligraf) had been applied to the wound. The arrows indicate where the sutures were placed. As you can see, there has been a considerable amount of wound contraction in only one week. Above right: One month after the application of Apligraf, the diabetic foot ulcer has healed completely.
Above left: A diabetic foot ulcer in an unusual location, on the dorsal surface of the first toe. Above right: In this photo, taken eight weeks after a single application of Apligraf, the wound has healed completely.
Above top left: Saline being applied in a Petri dish so that Apligraf can be easily removed from its culture medium. Above top right: Apligraf being lifted out of the dish with forceps. Above bottom left: Photo of a non-healing sacral ulcer that has been debrided down to subcutaneous tissue. Above bottom right: Four weeks after application of the Apligraf skin graft, the wound is healed.